The great majority of lentiviruses are exogenous, meaning that they are transmitted horizontally between individuals. Examples include the rabbit endogenous lentivirus type K RELIK , which became germ-line embedded approximately 12 million years ago Katzourakis et al. Molecular clocks derived from extant SIV sequences suggested that ancestral SIVs existed only a few hundreds of years ago Wertheim and Worobey , but it has long been suspected that such analyses may grossly underestimate deeper evolutionary timescales Sharp et al. Recent studies of SIV-infected monkeys on Bioko Island, Equatorial Guinea, partly substantiated this conclusion, showing that geographically isolated subspecies have been infected with the same type of SIV for at least 30, years and probably much longer Worobey et al. The endogenous viruses in lemurs reveal that the span of evolutionary history of primate lentiviruses as a whole is at least two orders of magnitude greater still. Thus, it is possible that at least some SIVs, such as those infecting four closely related species of African green monkeys Chlorocebus species , have coevolved with their respective hosts for an extended period of time, perhaps even before these hosts diverged from their common ancestor Jin et al. So far, SIV infections have only been found in African monkeys and apes, and so it seems likely that primate lentiviruses emerged in Africa sometime after the splits between lineages of African and Asian Old World monkeys, which are believed to have occurred around 6—10 million years ago Fabre et al. However, because neither Asian nor New World primates have been sampled exhaustively, the conclusion that SIVs are restricted to African primates must remain tentative, especially because none of these primate species has been examined for endogenous forms of SIV Ylinen et al.

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To field strip the P for cleaning, remove the magazine and ensure that the chamber is empty. Cock the hammer and then rotate the frame mounted takedown lever degrees downward. This is the small lever inletted into the forward left side of the frame. Pull the slide all the way rearward and lift the back of the slide off the frame’s slide rails. Then, run the slide forward off the fixed barrel. Pull the tapered recoil spring off the barrel. Note that the larger diameter end of this spring is forward.

That is all the disassembly required for cleaning and normal maintenance. Reassemble in reverse order.


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